8 results

EBSD mapping of shear zones strain gradient - deformation mechanisms

Objective : characterize the deformation mechanisms and the crystallographic fabrics within homogeneously deformed granitic samples.

EBSD mapping of brittle shear zones precursors

Collected date : Apr 2017

Objective : microtextural characterization within a shear zone brittle precursor

EBSD mapping of shear zones strain gradient - seismic anisotropy

Collected date : from Feb 2019 to Jun 2019

Objective : calculate the crystallographic preferred orientation (CPO) of each mineral phase in order to rebuild the elastic properties of the polyminéralic aggregates.

Microprobe analysis on a brittle shear zone precursor

Collected date : Jan 2017

Objective : compare the chemical compositions of minerals within the brittle precursor and in the host rock.

Quantitative X-ray mapping of brittle shear zones precursors

Collected date : May 2017

Objective : characterize the chemical zonings in plagioclase and garnet related to fluid-rock interactions within a shear zone precursor

New spiropyrrolothiazole derivatives bearing an oxazolone moiety as potential antidiabetic agent: Design, synthesis, crystal structure, Hirshfeld surface analysis, ADME and molecular docking studies

In a sustained search for novel and effective antihyperglycemics, a new series of fifteen isomeric oxazolone-fused dispiropyrrolothiazoles resulting from one-pot three component reaction between L-4-thiazolidine carboxylic acid, arylidene-oxazolones and isatin (or acenaphthenequinone) has been ...

Synthesis, antidiabetic activity and molecular docking study of rhodanine-substitued spirooxindole pyrrolidine derivatives as novel α-amylase inhibitors

In a sustained search for novel α-amylase inhibitors for the treatment of type 2 diabetes mellitus (T2DM), we report herein the synthesis of a series of nineteen novel rhodanine-fused spiro[pyrrolidine-2,3′-oxindoles]. They were obtained by one-pot three component [3 + 2] cycloaddition of stabilized ...

Diversity-oriented Synthesis of Spiropyrrolo[1, 2-a]isoquinoline Derivatives via Diastereoselective and Regiodivergent Three-component 1,3-Dipolar Cycloaddition Reactions: In vitro and in vivo Evaluation of the Antidiabetic Activity of Rhodanine Analogues

Collected date : from 2018 to 2021

An efficient diastereoselective route is developed to get access to novel spiropyrrolo[1,2-a]isoquinoline-oxindole skeletons by a one-potthree-component [3 + 2] cycloaddition reaction of (Z)-5-arylidene-1,3-thiazolidine-2,4-diones, isatin derivatives, and 1,2,3,4-tetrahydroisoquinoline (THIQ). ...

8 results

dat@uFC

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Université de Bourgogne, Université de Franche-Comté, UTBM, AgroSup Dijon, ENSMM, BSB, Arts des Metiers